Global Arc

A treatment of the quantitative tools to understand the human body. Course reviews cell biology and anatomy, then examines cells, tissues, and organs using principles from engineering kinetics and transport processes. Topics include: cell physiology; organ system physiology (including the cardiovascular, renal, and respiratory systems); and pathophysiology. Clinical treatments for human disease will also be analyzed.

This course covers major diseases (cancer, diabetes, heart disease, infectious diseases), the physical changes that inflict morbidity and mortality, the design constraints for treatment, and emerging technologies that take into account these physical hurdles. Taking the perspective of the design constraints on the system (that is, the mass transport and biophysical limitations of the human body), the course will survey recent results from the fields of drug delivery, gene therapy, tissue engineering, and nanotechnology. Two lectures.

Stoichiometry and mechanisms of chemical reaction rates, both homogeneous and catalytic; adsorption, batch, continuous flow, and staged reactors; coupling between chemical reaction rates and mass, momentum, and energy transport; stability; optimization of reactor design. Application to environmental and industrial problems. Two lectures, one preceptorial. Prerequisites: CBE 246, CBE 250, and CBE 341.

Introduction to chemical process flow-sheeting; process design, sizing and cost estimation of total processes; process economics; introduction to optimization, linear programming, integer programming, and nonlinear programming; heat integration methods, minimum utility cost, minimum number of units, network optimization. Two lectures, one laboratory. Prerequisites: CBE 341, CBE 346, and CBE 441.

A quantitative study of the principles of process dynamics and control. Dynamic behavior of chemical process elements; analysis and synthesis of linear feedback control systems with special emphasis on frequency response techniques and scalar systems. Two lectures. Prerequisite: MAE 305, which may be taken concurrently.

Introduction to engineering metabolism. The objective of this course is to introduce students to current techniques and challenges within the field of metabolic engineering. Specific topics include introduction to metabolism, transcriptional regulation, signal transduction, flux balance analysis, and metabolic flux analysis. Designed for upper division students in engineering, chemistry, and molecular biology. Two lectures. Prerequisites: MOL 214 or equivalent.

This independent work course requires students to complete a substantial piece of research and scholarship under the supervision and advisement of a Princeton faculty member. Projects may be experimental, computational, or theoretical -- topics selected by the students from suggestions by the faculty. The work requires sustained investment and attention throughout the semester, culminating in a written report and an oral defense. Departmental permission required.

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The senior thesis (498-499) is a year-long project in which students complete a substantial piece of research and scholarship under the supervision and advisement of a Princeton faculty member on an important problem or topic in chemical and biological engineering. Projects may be experimental, computational, or theoretical - topics selected by the students from suggestions by the faculty. While a year-long thesis is due in the student's final semester of study, the work requires sustained investment and attention throughout the academic year.

An experimental, computational, and theoretical study of an important problem or topic in chemical engineering. Topics selected by the students from suggestions by the faculty. Written thesis and oral defense required. The senior thesis is equivalent to a yearlong study and is recorded as a double course in the spring.