Global Arc

Continuation of CHM 301. The concepts introduced in CHM 301 will be extended to the structures and reactions of more complex molecules, with an emphasis on how organic chemistry provides the framework for understanding molecular processes in biology. The fundamental concepts of organic chemistry will be illustrated, as often as possible, with examples drawn from biological systems. Prerequisite: 301. Three lectures, one class, one three-hour laboratory.

An intro to quantum mechanics for students interested in the relevance to chemistry, molecular biology and energy science. A conceptual understanding is emphasized. Covers some historical development of quantum theory to show how quantum theory was a step-change in thinking. Examines ways quantum systems are different from classical systems. Includes the discussion of modern examples, including molecular electronic structure calculations, organic solar cells, photosynthesis, nanoscience, quantum computing, and quantum biology. Three lectures, one preceptorial. Prerequisites: CHM 201-202 or CHM 215; MAT 103-104; PHY 101-102 or PHY 103-104.

Introduction to chemical thermodynamics, statistical mechanics, and kinetics. Special emphasis on biological problems, including nerve conduction, muscle contraction, ion transport, enzyme mechanisms, and macromolecular properties in solutions. Prerequisites: CHM 201 and CHM 202, or CHM 207 and CHM 202, or CHM 215; MAT 104; PHY 101 and 102, or PHY 103 and 104; or instructor's permission. Three lectures, one class.

A one-semester introduction to the organic chemical reactions of greatest biological importance. Covers organic mechanisms underlying fundamental metabolic reactions and introduces engineering approaches for analyzing networks of such reactions. For biology or engineering students, this course is an alternative to the standard two-semester organic chemistry sequence (CHM301 and 302/304). Satisfies the organic chemistry requirement for MOL and CBE, but not for CHM majors. Provides appropriate background for subsequent studies in biochemistry.

This course addresses the principles of experimental design, data acquisition, analysis and interpretation, and presentation of experimental results. Students are exposed to a broad range of quantitative laboratory methods in preparation for thesis work in chemical sciences. Typical laboratory exercises include inorganic synthesis, physical characterization, spectroscopy, kinetics, thermodynamics, instrument design and computational chemistry. Prerequisites: CHM 202, 204 or 215 or equivalent. CHM 373 prerequisite or concomitant enrollment in CHM 373 required. Two lectures and two three-hour laboratories per week.

Fundamental principles of modern analytical tools including spectroscopy, chromatography & electrochemical methods will be introduced. These techniques will be used to design experiments. Applications of instrumental methods such as molecular properties will be rehearsed through quantitative analysis of example spectra. Data treatments using statistical methods for proper reporting of information with precision, accuracy, and uncertainty will be covered. Relationships between physical parameters will also be discussed from a statistical point of view. Computational Chemistry will be integrated into data analysis.

Applies the principles of organic chemistry to biochemistry. Explores enzymology through the lenses of physical organic chemistry, bioinorganic chemistry, catalysis. Covers how proteins orchestrate the reactivity of functional groups, the range of cofactors employed to extend the scope and diversity of biocatalysis, enzymatic systems controlled by their kinetics, and how knowledge of enzyme reaction mechanisms enables modern drug design. Prerequisites: CHM 301 and CHM 302/CHM 304. Two 90-minute lectures, one preceptorial.

Introduction to quantum theory, atomic and molecular structure, and spectroscopy. This course will emphasize the development of fundamental underlying principles and illustrative examples. Prerequisites: 202, 204, or 215; MAT 201 or 203 (required); MAT 202 or 204 (very helpful, even if taken concurrently); PHY 103 (may be taken concurrently) or AP Physics. Three lectures, one preceptorial.

Statistical thermodynamics, kinetics, and molecular reaction dynamics. Prerequisites: background in thermodynamics as developed in CHM 202, CHM 204, or CHM 215; MAT 201 or equivalent. Two 90-minute lectures.

Survey of the principles of the structure and properties of non-molecular solids. Space group symmetry, structure determination by x-ray, and neutron diffraction. Introduction to electron microscopy. Important structure types in metals and oxides. Pauling Rules, solid solutions, nonstoichiometry, and defect chemistry. Two 90-minute lectures.