This combined lecture and seminar class explores neural circuit mechanisms of neuropsychiatric disorders through the lens of animal models. We examine the molecular, cellular, and computational basis of conditions like depression, anxiety, addiction, and schizophrenia. After reviewing core brain systems (basal ganglia, amygdala, PFC, hippocampus) and neuromodulators (dopamine, serotonin), the class transitions to weekly disease-specific units. By engaging deeply with primary literature, you will evaluate biological hypotheses regarding how dysfunctions arise within the circuitry underlying learning and emotion.
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